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    Did you mean Androgen Receptor Antagonists?
    GlossaryAndrogen Receptor Antagonists

    block male hormones like testosterone from affecting tissues

    Androgen Receptor Antagonists, also known as antiandrogens, are medications that block the action of androgens, which are male sex hormones like testosterone. These drugs work by binding to androgen receptors, preventing androgens from exerting their effects on tissues, and are commonly used in the treatment of conditions like prostate cancer, androgenic alopecia (male-pattern baldness), and certain types of acne.

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      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

      learn Fluridil

      a topical anti-androgen with less systemic involvement

      learn Bicalutamide

      a nonsteroidal anti-androgen, most commonly used orally for women

      learn GT20029

      research compound made to degrade androgen receptors in scalp

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      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 1 month ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community How to know if shedding is from tren or minoxidil?

      in Minoxidil  5 upvotes 6 months ago
      The user started using trenbolone and minoxidil simultaneously and experienced increased hair shedding, unsure which is causing it. Replies suggest both drugs could cause hair loss, with one advising to stop trenbolone to protect hair and another indicating minoxidil is unlikely the cause due to the timing.

      community How much dht does Nizoral shampoo block?

      in Ketoconazole  101 upvotes 3 years ago
      Hair loss treatments discussed include Minoxidil, Finasteride, RU58841, and Nizoral shampoo. Nizoral's effectiveness is debated, with some suggesting it works as a weak antagonist for androgen receptors, while others attribute its benefits to anti-fungal and anti-inflammatory properties.