learn Azelaic Acid
acid used for antimicrobial, anti-inflammatory and anti-androgenic properties
Search
forLearn
5 / 11 resultslearn Overview
learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
learn Stem Cell Factor
learn Alpha linolenic acid
Research
5 / 1000+ resultsresearch The Viscoelastic Properties of Chemically Modified alpha-Keratins in Human Hair
The study investigated the viscoelastic properties of human hair after chemical modifications, specifically esterification and disulfide reduction with alkylation. Esterification was found to plasticize the hair matrix and affect the stability of intermediate filaments (IFs), with the alkyl chain length influencing plasticizing efficiency. Disulfide reduction and alkylation significantly impacted the matrix by reducing water content-dependent glass transition and IF stability, although hydrophobic interactions at high water content helped maintain IF integrity. Mechanical tests showed some restoration of stability after propylation. The study suggested that hydrophobic interactions play a role in stabilizing hair fibers at higher relative humidities and water contents, and future research could further elucidate the specific effects of these modifications.
research DSC-investigations of alpha-keratins and the specific effects of chemical treatments on human hair
research Recurrent functional divergence of early tetrapod keratins in amphibian toe pads and mammalian hair
The study investigated the evolutionary origin of proteins in the toe pads of the tree frog Hyla cinerea, which are crucial for adhesion in arboreal habitats. Researchers identified five alpha keratins as the main structural proteins in these toe pads. Phylogenetic analyses indicated that these keratins originated from different lineages in an early tetrapod ancestor. In mammals, these keratins evolved to become the major types found in hair. The ancestral keratins were likely expressed in areas needing skin reinforcement in early tetrapods and later diverged to support different adaptive structures in amphibians and mammals.
research A Rapid Extraction Procedure of Human Hair Proteins and Identification of Phosphorylated Species.
A new method quickly extracts and identifies proteins from hair and other keratin sources.
research Proteomic Tools for the Investigation of Human Hair Structural Proteins and Evidence of Weakness Sites on Hair Keratin Coil Segments
Hair proteins have weak spots in their α-helical segments.
Community Join
5 / 504 resultscommunity New & Improved Hair Growth Stack for Maximum Results
A user shared a hair growth stack using minoxidil sulfate, valproic acid, bimatoprost, blue copper peptide, and other ingredients, emphasizing a gel-based formula for better skin tolerance. Another user suggested adding a 5-alpha-reductase inhibitor like finasteride or dutasteride for more effective long-term results.
community Is tazarotene potentially better than tretinoin in combination with topical minoxidil?
Tazarotene may be more effective than tretinoin when combined with topical minoxidil for hair loss due to its selective binding to RAR-beta and gamma, though it can cause irritation. Tazarotene's potency can lead to indirect inflammatory reactions despite potentially causing less irritation than tretinoin.
community here is why isotretinoin might cause hair loss and maybe why dupa happens.
Isotretinoin may cause hair loss by increasing DHT through a precursor androgen, DHEAS. Treatments like topical antiandrogens (RU58841, pyrilutamide) and drugs increasing PPAR-y expression (pioglitazone) might prevent this hair loss.
community Summary of Procapil video by Haircafe
Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.
community Bryan (the guy who reversed aging) shares treatment that reversed his hair loss
A person improved hair loss from Norwood 3 to Norwood 2 using a topical formula with minoxidil, dutasteride, and tretinoin, plus oral minoxidil and red light therapy. There is skepticism about the treatment's effectiveness and concerns about misleading comparison photos.