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an anticonvulsant repurposed for hair loss via histone inhibition
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compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles
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research Valproic Acid Induces Hair Regeneration in Murine Model and Activates Alkaline Phosphatase Activity in Human Dermal Papilla Cells
Valproic Acid helps regrow hair in mice and activates a hair growth marker in human cells.
research Alkaline Ceramidase 1 Protects Mice from Premature Hair Loss by Maintaining the Homeostasis of Hair Follicle Stem Cells
Alkaline Ceramidase 1 prevents early hair loss in mice by keeping hair follicle stem cells balanced.
research Overexpression of Alkaline Phosphatase Improves the Hair-Inductive Capacity of Cultured Human Dermal Papilla Spheres
Increasing alkaline phosphatase in human skin cells helps to grow more hair.
research The Interaction of Hair Fibers with Alkali Bromide Solutions
Hair absorbs alkali bromide salts and water, affecting its structure, with absorption decreasing at higher temperatures.
research Effects of the Anti-Androgen Finasteride on 5α-Reduction of Androgens in the Presence of Progesterone in Human Gingival Fibroblasts: Modulatory Actions of the Alkaline Phosphatase Inhibitor Levamisole
Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.
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5 / 22 resultscommunity Increasing activity of the sult1a1 enzyme via alkalizing agent and tretinoin for better response to topical minoxidil
Increasing the sult1a1 enzyme on the scalp may improve response to topical minoxidil. The user suggests using a baking soda solution, DMSO, and tretinoin to enhance enzyme activity and minoxidil effectiveness.
community Topical minoxidil brand (and form of application) matters. You can be a hyper-responder to one product and a non-responder to another.
Different minoxidil formulations affect hair growth and side effects. Higher propylene glycol and pH levels improve effectiveness but can cause scalp irritation.
community DIY Shed treatment & thick regrowth, Vitamin C shampoo
DIY hair loss treatment with vitamin C in shampoo reduced shedding and promoted regrowth, benefiting both the original poster and their wife.
community Ejaculation and Oxytocin are responsible for Hair loss
The conversation discusses the idea that ejaculation and oxytocin might cause hair loss. It mentions treatments like Minoxidil, finasteride, and RU58841.
community People who don’t microneedle, why?
Microneedling is often combined with minoxidil for hair growth, but concerns about scalp damage, pain, and effectiveness deter some users. Alternatives like finasteride, dutasteride, tretinoin, and laser treatments are preferred by others.