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5 / 66 resultslearn Alfatradiol
a synthetic estrogen used topically as an anti-androgen
learn Fluridil
a topical anti-androgen with less systemic involvement
learn SCUBE3
a signaling molecule from dermal papilla cells being actively researched
learn RU58841
a potent but unapproved and potentially problematic topical anti-androgen
Research
5 / 1000+ results
research Sexual Dysfunction Related to Drugs: A Critical Review. Part V: Alpha-Blocker and 5-ARI Drugs
α-Blockers and 5-ARIs for BPH can cause sexual dysfunction, including erectile and ejaculatory issues.
research A Retrospective Study of Clinical Outcomes of Alpha-Blocker or Finasteride Monotherapy Followed by Combination Therapy: Determination of the Period of Combination Therapy of Alpha-Blocker and Finasteride
Combination therapy for 9+ months maintains symptom improvements after stopping alpha-blockers or finasteride.
research Alpha-1A Blockers Combined with Prozac for the Treatment of Premature Ejaculation
Combining α1A-blockers with Prozac is more effective for treating premature ejaculation than Prozac alone.
research Finasteride Reduces the Preventive Effect of Uroselective α1A-Blockers Against Cancellous Bone Disorders Induced by Androgen Deficiency in Rats
Finasteride weakens the bone-protective effects of certain blockers in low androgen conditions.
research Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque
Testosterone can slow hair growth in adult monkeys, but a blocker called RU 58841 can counteract this and potentially help hair regrow.
Community Join
5 / 1000+ resultscommunity A New Hair Loss Drug Could Cure Balding and Reverse Graying
ABS-201, a prolactin receptor blocker, shows promise in reversing hair loss and graying, with early success in macaques. Current treatments like finasteride, minoxidil, and RU58841 are still widely used, but new options like PP405 are eagerly anticipated.
community What do you guys think about my foundation?
The user had a hair transplant and uses oral minoxidil, a red laser therapy helmet, fish oil, collagen, and sardines for hair thinning but avoids finasteride due to side effect concerns. Many suggest these methods may not be effective long-term without a DHT blocker.
community (MTF 35) Results of 18 Months of HRT
A transgender woman experienced significant hair regrowth after 18 months of hormone replacement therapy (HRT) with estrogen and bicalutamide. The discussion notes HRT's effectiveness for hair regrowth but warns against its use for cisgender men due to feminizing effects.
community My friend is so terrified of balding, he started microdosing estrogen…
A person is microdosing estrogen for hair loss after finasteride and dutasteride failed, risking feminizing effects. Alternatives like minoxidil, RU58841, or hair transplants are suggested.
community First one is before, second one is after. Is it getting better?
A user shared their experience using Minoxidil for 5 months and finasteride for 3 weeks, with inconsistent microneedling. Another user advised waiting at least 6 months to see results.