Absence of Vitamin D Receptor-Mediated PPARγ Suppression Causes Alopecia in VDR-Null Mice

December 2016 in “ The FASEB Journal ”

Saini Vaibhav, Zhao Heng-guang, Petit, Elizabeth T., Gori Francesca, Demay Marie B.

vitamin D receptor VDR alopecia keratinocyte stem cell KSC PPARγ PGC1β LPL transcriptional suppressor hair growth hair loss stem cells gene expression

Studysummary This study found that the absence of vitamin D receptor-mediated suppression of PPARγ expression causes hair loss in VDR-null mice.

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