The Evolution of Healthy Skin to Acne Lesions: A Longitudinal, In Vivo Evaluation with Reflectance Confocal Microscopy and Optical Coherence Tomography

    Marco Manfredini, Vincenzo Bettoli, G. Sacripanti … Giovanni Pellacani
    Studysummary This study found that acne lesion formation involves early hyperkeratinization and inflammation around hair follicles, creating a self-sustaining cycle that may progressively worsen acne.
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    Research cited in this study 3

    1. Host-Microbiome Interactions and Recent Progress in Understanding the Biology of Acne Vulgaris Microbiome · 2018
    2. Sex Hormones and Acne: The Role of the Skin as an Endocrine Organ Clinics in dermatology · 2016
    3. Strategic Targets in Acne: The Comedone Switch in Question Dermatology · 2015

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    1. Studying the Efficacy of a New Radical Treatment for Acne Vulgaris Using a Surgical Technique Journal of dermatological treatment · 2019