Bicalutamide Improves Minoxidil-Induced Hypertrichosis in Female Pattern Hair Loss: A Retrospective Review of 35 Patients

    November 2021 in “ Journal of The American Academy of Dermatology ”
    Anthony Moussa, Ahmed Kazmi, Laita Bokhari, Rodney Sinclair
    Studysummary This article notes that low-dose systemic minoxidil combined with antiandrogen therapy is effective for treating female pattern hair loss, though hypertrichosis can occur in a significant percentage of patients.
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    Research cited in this study 4

    1. Safety of Low-Dose Oral Minoxidil Treatment for Hair Loss: A Systematic Review and Pooled Analysis of Individual Patient Data Dermatologic Therapy · 2020
    2. Bicalutamide: A Potential New Oral Antiandrogenic Drug for Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2020
    3. Female Pattern Hair Loss: A Pilot Study Investigating Combination Therapy with Low-Dose Oral Minoxidil and Spironolactone International Journal of Dermatology · 2017
    4. Minoxidil May Suppress Androgen Receptor-Related Functions Oncotarget · 2014

    Related research 6

    1. Bicalutamide Improves Minoxidil-Induced Hypertrichosis in Female Pattern Hair Loss: A Retrospective Review of 35 Patients Journal of The American Academy of Dermatology · 2021
    2. Characterization and Management of Hypertrichosis Induced by Low-Dose Oral Minoxidil in the Treatment of Hair Loss Journal of The American Academy of Dermatology · 2020
    3. Treatments of Hereditary Hair Loss (Alopecia) 2018
    4. Clinical Updates in Hair Dermatologic Clinics · 1997
    5. Topical Minoxidil for Hair Growth in Alopecia Areata and Androgenetica Drugs · 1987
    6. Topical Minoxidil in Extensive Alopecia Areata, Including 3-Year Follow-Up Dermatology · 1987