Alopecia Areata and Malignancies: Uncertainties Clarified by a Large-Scale Population-Based Study

October 2024 in “ Archives of Dermatological Research ”

Khalaf Kridin, Rimma Laufer-Britva, Francisco Jiménez Otárola, Arnon D. Cohen, Baruch Kaplan, Anna Lyakhovitsky

alopecia areata hematological malignancies non-Hodgkin lymphoma alopecia totalis alopecia universalis

Studysummary This study found that alopecia areata was associated with an increased risk of hematological malignancies, particularly non-Hodgkin lymphoma, but not with solid malignancies, except in certain severe cases.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

View this study on link.springer.com →

Discuss this study in the Community →

Research cited in this study

11 / 11 results

research Alopecia Areata: What's New in the Epidemiology, Comorbidities, and Pathogenesis?

49 citations , October 2023 in “Journal of Dermatological Science”

Incidence Rates of Infections, Malignancies, Thromboembolism, and Cardiovascular Events in an Alopecia Areata Cohort from a US Claims Database

research Incidence Rates of Infections, Malignancies, Thromboembolism, and Cardiovascular Events in an Alopecia Areata Cohort from a US Claims Database

1 citations , June 2023 in “Dermatology and therapy”

This study found that patients with alopecia areata had a higher incidence rate of herpes simplex infection compared to matched individuals without the condition.

research Alopecia Areata: An Updated Review for 2023

91 citations , May 2023 in “Journal of Cutaneous Medicine and Surgery”

Alopecia Areata affects 2% globally, with treatments like essential oils, garlic, and JAK inhibitors showing promise, but more research is needed.

research Alopecia Areata: An Update on Etiopathogenesis, Diagnosis, and Management

290 citations , August 2021 in “Clinical Reviews in Allergy & Immunology”

JAK inhibitors show promise for treating alopecia areata, but more research is needed.

research Cancer Risk by the Subtype of Alopecia

9 citations , June 2018 in “Scientific Reports”

This study reported that patients with alopecia areata or alopecia totalis/universalis have a slightly increased overall cancer risk compared to controls, with specific increases in thyroid, bladder, and prostate cancers depending on the alopecia type.

research Cancer Risk in Patients with Alopecia Areata: A Nationwide Population-Based Matched Cohort Study

15 citations , March 2018 in “Cancer Medicine”

This study found that alopecia areata patients had a slightly decreased overall cancer risk, with significantly lower risks for some cancers but higher risks for lymphoma, breast, kidney, and urinary bladder cancers.

research Comorbidities in Patients with Alopecia Areata

56 citations , March 2017 in “Journal of the American Academy of Dermatology”

Alopecia areata patients often have eczema, thyroid issues, vitamin-D deficiency, and anemia.

research Late-Onset Alopecia Areata: A Retrospective Cohort Study

7 citations , January 2017 in “Dermatology”

In this study, late-onset alopecia areata in Israeli patients was predominantly observed in females with mild disease, showing a high rate of complete hair regrowth but frequent relapses.

research Alopecia Areata as a Paraneoplastic Syndrome of Hodgkin’s Lymphoma: A Case Report

10 citations , April 2014 in “Molecular and Clinical Oncology”

This case report describes a 46-year-old male whose alopecia areata preceded and resolved with treatment for stage IVB classical Hodgkin's lymphoma, highlighting AA as a potential indicator of underlying malignancy, although such cases are rare and not well-characterized.

research Alopecia Universalis Associated with Cutaneous T Cell Lymphoma

15 citations , January 2014 in “Dermatology”

This case report describes alopecia universalis-like hair loss occurring in two patients with cutaneous T cell lymphoma, providing clinical, dermoscopic, and pathologic features to help differentiate it from alopecia areata universalis.

research Late-Onset Alopecia Areata: A Retrospective Study of 73 Patients from Taiwan

21 citations , February 2012 in “Journal of the European Academy of Dermatology and Venereology”

This study found that late-onset alopecia areata is more common in women and tends to present with milder symptoms, with some patients achieving complete hair regrowth in mild cases.