Current Trends in the Clinical Application of Tissue-Engineered Scaffolds for Cutaneous Wound Healing: A Narrative Review

July 2026 in “ Current Problems in Surgery ”

Hiu Yeung Chau, Mei‐Chun Chen, Kai Hsia, Chih‐Hsun Lin

tissue-engineered scaffolds cutaneous wound healing biologically derived tissues natural polymers synthetic polymers composites electrospinning 3D bioprinting nanotechnology cellular infiltration vascularization infection smart skin substitutes functionally graded skin substitutes

Studysummary This narrative review reports that tissue-engineered scaffolds for wound healing generally match standard care outcomes, with some trials indicating faster healing and improved scar quality, despite challenges like limited cellular infiltration and inadequate vascularization.

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