TREATMENT OF HAIR LOSS

January 2000 in “ วารสารเภสัชวิทยา (Thai Journal of Pharmacology) ”

Srisombat Nawanopparatsakul

androgenetic alopecia alopecia areata finasteride minoxidil FDA-approved drugs Propecia Rogaine

TLDR Early treatment with finasteride and minoxidil can effectively reverse hereditary hair loss.

The document discussed hereditary hair loss, focusing on androgenetic alopecia and alopecia areata, which could be reversed with early and correct treatment. It highlighted finasteride and minoxidil as FDA-approved drugs for these conditions, noting that they had different mechanisms of action but were clinically proven to be effective, especially when used together. The document emphasized the need for ongoing research to develop new treatments or repurpose existing drugs for hair loss.

View this study on tci-thaijo.org →

Discuss this study in the Community →

Research cited in this study

14 / 14 results

research Treatment of Hair Loss

370 citations , September 1999 in “The New England Journal of Medicine”

Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.

research Finasteride

125 citations , January 1999 in “Drugs”

Finasteride effectively treats baldness but may cause sexual side effects.

research Finasteride in the Treatment of Men with Androgenetic Alopecia

581 citations , October 1998 in “Journal of The American Academy of Dermatology”

Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.

research Hair Regrowth

118 citations , April 1998 in “Dermatologic Clinics”

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia

research Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia

416 citations , September 1997 in “Journal of Investigative Dermatology”

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

research Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia

143 citations , October 1996 in “Dermatologic Clinics”

Too much androgen can cause hair loss; finasteride may help.

research Guidelines of Care for Androgenetic Alopecia

37 citations , September 1996 in “Journal of The American Academy of Dermatology”

Treat genetic hair loss early with FDA-approved medications and consider hair transplantation.

research In Vivo Time-Dependent Inhibition of Human Steroid 5α-Reductase by Finasteride

29 citations , January 1996 in “Journal of Pharmaceutical Sciences”

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

research Androgenetic Alopecia: An Autosomal Dominant Disorder

80 citations , January 1995 in “The American Journal of Medicine”

Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.

research Androgenetic Alopecia in the Female

82 citations , March 1994 in “Archives of Dermatology”

2% topical minoxidil effectively treats female hair loss with minimal side effects.

research Status of Medical Treatment for Androgenetic Alopecia

13 citations , October 1993 in “International Journal of Dermatology”

Minoxidil effectively promotes hair regrowth in younger patients with small balding areas.

research Finasteride

86 citations , July 1993 in “Drugs”

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

research The Effect of Finasteride in Men with Benign Prostatic Hyperplasia

1040 citations , October 1992 in “The New England Journal of Medicine”

Finasteride effectively treats BPH but may increase sexual dysfunction risk.

research Biology of Hair Growth

46 citations , May 1986 in “Seminars in Reproductive Medicine”

Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.

Related Research

17 / 17 results

research Hair Transplantation in Androgenetic Alopecia

June 2021 in “Cosmoderma”

Hair transplantation techniques have improved, making the process safer and more effective with less visible scarring.

research Surgical Interventions for Androgenetic Alopecia

March 2021 in “Dermatological reviews”

Hair transplant works well, but needs more research for better results.

research Microneedling: A Novel Therapeutic Approach for Androgenetic Alopecia, A Review of Literature

13 citations , September 2020 in “Dermatologic Therapy”

Microneedling may help hair loss, but needs more research.

research New Drugs Under Investigation for the Treatment of Alopecias

26 citations , January 2019 in “Expert Opinion on Investigational Drugs”

New treatments for hair loss show promise, but more research is needed to confirm their safety and effectiveness.

research Off-Label Use of Topical Minoxidil in Alopecia: A Review

32 citations , January 2019 in “American Journal of Clinical Dermatology”

Minoxidil helps treat eyebrow thinning, monilethrix, early hair loss, and shortens chemo-related hair loss.

research Hair Disorders, Treatment and Care: An Overview

November 2015

Effective treatments and proper care can manage hair disorders.

research Treatment Options for Alopecia

17 citations , August 2015 in “Expert Opinion on Pharmacotherapy”

The document concludes that oral finasteride and topical minoxidil are effective for genetic hair loss, while other treatments for different types of hair loss show promise but need more research.

research A Review of Medical and Surgical Treatment Options for Androgenetic Alopecia

41 citations , September 2014 in “JAMA Facial Plastic Surgery”

Use finasteride, minoxidil, and follicular unit transplantation for hair loss treatment.

research Hair Restoration Approaches for Early Onset Male Androgenetic Alopecia

2 citations , September 2013 in “Journal of Cosmetic Dermatology”

Hair restoration combines drugs and follicular unit grafting for natural, long-lasting results.

research Nonsurgical Therapy for Hair Loss

14 citations , August 2013 in “Facial Plastic Surgery Clinics of North America”

Some nonsurgical hair loss treatments are effective, especially if started early.

research Female Pattern Alopecia: Current Perspectives

42 citations , August 2013 in “International Journal of Women's Health”

Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.

research Promising Therapies for Treating and Preventing Androgenic Alopecia

36 citations , June 2012 in “PubMed”

There are potential treatments for pattern baldness, but more research is needed to confirm their effectiveness.

research Management of Hair Loss Diseases

14 citations , December 2010 in “Dermatologica Sinica”

New treatments for hair loss show promise, but more development is needed, especially for tough cases.

research Treatment Strategies for Alopecia

34 citations , April 2009 in “Expert Opinion on Pharmacotherapy”

Some treatments work for common baldness, but there's less evidence for other hair loss types, and more research is needed.

research Male Androgenetic Alopecia: Medical and Surgical Treatments

9 citations , February 2005 in “The Journal of Men's Health & Gender”

Finasteride effectively treats male hair loss, increasing length and thickness.

research Androgenetic Alopecia: Combining Medical and Surgical Treatments

15 citations , October 2003 in “Dermatologic Surgery”

Minoxidil, finasteride, and hair transplantation combined give best results for hair loss.

research Management of Androgenetic Alopecia

22 citations , May 2000 in “American Journal of Clinical Dermatology”

Treatments for common hair loss include minoxidil, finasteride, and hair transplantation.