The Pathogenesis of Alopecia Areata
October 1996
in “
Dermatologic Clinics
”
alopecia areata genetic predisposition HLA haplotypes HLA-DR4 HLA-DR5 chromosome 21 Down syndrome cytokines interleukin 1 receptor antagonist gene autoimmunity autoimmune disorders autoantibodies corticosteroids cyclosporin A hair regrowth atopy psychological stress trauma infection immune system dysfunction hair follicle physiology alopecia areata genetic predisposition HLA-DR4 HLA-DR5 Down syndrome cytokines interleukin 1 receptor antagonist gene autoimmunity autoimmune disorders autoantibodies corticosteroids cyclosporin A hair regrowth atopy psychological stress trauma infection immune system dysfunction hair follicle physiology
Studysummary This review discusses androgenetic alopecia and alopecia areata through a systems biology lens, emphasizing the role of multi-omics data integration to explore molecular mechanisms and potential therapeutic strategies, but offers no new clinical results.
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