The genetics of alopecia areata: What's new and how will it help our patients?

    May 2011 in “ Dermatologic therapy
    Lynn Petukhova, Rita Cabral, Julian Mackay‐Wiggan, Raphael Clynes, Angela M. Christiano
    TLDR New genetic discoveries in alopecia areata could lead to better treatments.
    The document from May 01, 2011, discusses the prevalence of alopecia areata (AA) in the United States, affecting an estimated 5.3 million people, and highlights the lack of evidence-based treatments for this autoimmune disease. The authors report on the completion of the first genome-wide association study (GWAS) for AA, which identified at least eight genomic regions associated with the condition. This study revealed a set of genes, some of which are already known in the context of other autoimmune diseases and have targeted therapies available or in development. These genetic insights are expected to lead to the development of new, effective treatments for AA and mark the beginning of an era of translational research in the field based on these genetic findings.
    View this study on onlinelibrary.wiley.com →

    Cited in this study

    1 / results
      Interventions for alopecia areata

      research Interventions for alopecia areata

      164 citations ,   April 2008 in “Cochrane library”
      Current treatments for alopecia show no significant long-term benefits.