TLDR WS Biotin, a new form of D-Biotin, improves water solubility and shows potential for hair and skin care without being toxic at low levels.
The study developed and evaluated WS Biotin, a new encapsulated form of D-Biotin with 40 times improved water solubility, for use in hair and skin treatments. The microcapsules contained 46.1% D-Biotin and showed no significant cytotoxicity at concentrations below 0.1%. WS Biotin was found to promote follicular keratinocyte proliferation, enhance the expression of hair-associated keratins KRT40 and KRT85, and upregulate the expression of hair growth-related genes VEGF, FGF7, and IGF1, suggesting its potential in promoting hair maintenance and improving hair shaft strength. Additionally, WS Biotin demonstrated a potential skin-lightening effect by triggering a dose-dependent decrease in melanin levels. The study indicates the need for enhanced delivery strategies for biotin due to the high doses used.View this study on onlinelibrary.wiley.com →
Both brands of biotin and dexpanthenol injections improved hair loss, with Bayer also increasing the ratio of thick to thin hairs.
Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.