The Formation of Hair Follicle induced by Immortalized Human Dermal Papilla Cell Line in vivo

The study investigated the ability of the immortalized human dermal papilla cell line, DPC-hTERT, to induce hair follicle formation in vivo. Researchers co-injected DPC-hTERT cells at passage 30 with freshly isolated hair follicle epithelial cells into nude mice. The results showed that this combination formed hair follicle-like structures that expressed hair follicle-specific keratin. The conclusion was that DPC-hTERT retained the normal function of dermal papilla cells and could induce hair follicle-like structures in vivo.