Significant Hair Regrowth With 5% Topical Minoxidil in a Child With Marie Unna Hereditary Hypotrichosis Caused by a Recurrent HRURF Variant

    August 2025 in “ Journal of Cosmetic Dermatology ”
    Can Cui, Xi Chen, Yingzi Zhang … Aihua Wei
    Studysummary This study reported significant short-term scalp hair regrowth and increased density in a 4-year-old with Marie Unna hereditary hypotrichosis following topical 5% minoxidil treatment, suggesting its potential benefit in this condition.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 5

    1. Successful Treatment of Hereditary Hypotrichosis Simplex by Platelet Rich Plasma Injection With Topical Minoxidil 2% Journal of Dermatological Treatment · 2023
    2. Gene Detection in a Family With Monilethrix and Treatment With 5% Topical Minoxidil Skin research and technology · 2022
    3. Minoxidil Induced Hypertrichosis in a 2-Year-Old Child F1000Research · 2013
    4. Marie Unna Hereditary Hypotrichosis: Identification of a U2HR Mutation in the Family from the Original 1925 Report Journal of the American Academy of Dermatology · 2011
    5. Loss-Of-Function Mutations of an Inhibitory Upstream ORF in the Human Hairless Transcript Cause Marie Unna Hereditary Hypotrichosis Nature Genetics · 2009

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