Safety and Efficacy of Rice Bran Supercritical CO2 Extract for Hair Growth in Androgenic Alopecia: A 16-Week Double-Blind Randomized Controlled Trial

    Jae-Suk Choi, Jae Yong Park, Woi-Sook Moon … Miryung Kim
    Studysummary This study found that a 16-week dermal application of rice bran extract significantly increased hair density and diameter in male androgenic alopecia patients without causing adverse reactions.
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    Research cited in this study 18

    1. Acute Dermal and Ocular Irritation Testing of Rice Bran Supercritical CO2 Extract (RB-SCE) and 0.5% RB-SCE Essence Product Toxicology and Environmental Health Sciences · 2015
    2. Genotoxicity of Rice Bran Oil Extracted by Supercritical CO2 Extraction Biological & pharmaceutical bulletin · 2014
    3. In Vivo Hair Growth-Promoting Effect of Rice Bran Extract Prepared by Supercritical Carbon Dioxide Fluid Biological & Pharmaceutical Bulletin · 2013
    4. Efficacy of Korean Red Ginseng in the Treatment of Alopecia Areata Journal of Ginseng Research · 2012
    5. Hair: What Is New in Diagnosis and Management? Dermatologic Clinics · 2012
    6. 5α-Reductase Type 1 Inhibition of Oryza Sativa Bran Extract Prepared by Supercritical Carbon Dioxide Fluid Journal of Supercritical Fluids · 2011
    7. Female Pattern Hair Loss: Current Treatment Concepts PubMed · 2007
    8. The Importance of Dual 5α-Reductase Inhibition in the Treatment of Male Pattern Hair Loss: Results of a Randomized Placebo-Controlled Study of Dutasteride Versus Finasteride Journal of The American Academy of Dermatology · 2006
    9. Finasteride in the Treatment of Androgenetic Alopecia Expert Opinion on Pharmacotherapy · 2004
    10. A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2004
    11. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    12. Allergic Contact Dermatitis to Topical Minoxidil Solution: Etiology and Treatment Journal of The American Academy of Dermatology · 2002
    13. Evaluation of Sexual Function in Subjects Taking Finasteride for the Treatment of Androgenetic Alopecia Journal of The European Academy of Dermatology and Venereology · 2001
    14. The Prevalence and Types of Androgenetic Alopecia in Korean Men and Women British Journal of Dermatology · 2001
    15. The First Clinical Trial of Topical Application of Procyanidin B-2 to Investigate Its Potential as a Hair Growing Agent PTR. Phytotherapy research/Phytotherapy research · 2001
    16. Hair Regrowth Dermatologic Clinics · 1998
    17. Photographic Documentation of Hair Growth in Androgenetic Alopecia Dermatologic Clinics · 1996
    18. Contact Dermatitis in Reaction to 2% Topical Minoxidil Solution Journal of The American Academy of Dermatology · 1991

    Related research 1

    1. Safety and Efficacy of Rice Bran Supercritical CO2 Extract for Hair Growth in Androgenic Alopecia: A 16-Week Double-Blind Randomized Controlled Trial Biological & Pharmaceutical Bulletin · 2015