To Evaluate the Role of Interleukin-6 in Alopecia Areata

The study conducted at the Sindh Institute of Skin Disease investigated interleukin-6 levels in 100 subjects, comprising 50 alopecia areata patients and 50 healthy controls. Results showed that interleukin-6 concentrations were significantly higher in alopecia areata patients compared to controls, indicating a potential role of this pro-inflammatory cytokine in the disease. The study found no significant difference in interleukin-6 levels between genders, but levels were highest in patients aged 11-20 years. This suggests that interleukin-6 may be involved in the pathogenesis of alopecia areata.