Role of -catenin in Epidermal Stem Cell Expansion, Lineage Selection, and Cancer
January 2008
in “
Cold Spring Harbor Symposia on Quantitative Biology
”
Research cited in this study
16 / 16 resultsresearch Activation of Beta-Catenin Signaling Programs Embryonic Epidermis to Hair Follicle Fate
Activating β-catenin can turn skin cells into hair follicles.
research Epidermal Notch Signaling: Differentiation, Cancer, and Adhesion
Notch signalling helps skin cells differentiate and prevents tumors.
research The Vitamin D Receptor Is Required for Mouse Hair Cycle Progression but Not for Maintenance of the Epidermal Stem Cell Compartment
Vitamin D Receptor is needed for hair growth in mice but not for skin stem cell maintenance.
research The Vitamin D Receptor Is a Wnt Effector That Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult Epidermis
Vitamin D receptor helps control hair growth and could be used to treat certain skin tumors.
research Sic Transit Gloria: Farewell to the Epidermal Transit Amplifying Cell?
New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
research Vitamin D Receptor Is Essential For Normal Keratinocyte Stem Cell Function
Vitamin D receptor is crucial for normal hair growth and preventing hair loss.
research Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding
Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.
research Long-Term Renewal of Hair Follicles from Clonogenic Multipotent Stem Cells
Adult stem cells from rat whisker follicles can regenerate hair follicles and sebaceous glands.
research Transient Activation of Beta-Catenin Signaling in Adult Mouse Epidermis Induces New Hair Follicles, Continuous Activation Maintains Tumors
Temporary activation of β-catenin can create new hair follicles, but ongoing activation is needed to keep hair follicle tumors.
research Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge
The K15 promoter effectively targets stem cells in the hair follicle bulge.
research Manipulation of Stem Cell Proliferation and Lineage Commitment: Visualization of Label-Retaining Cells in Wholemounts of Mouse Epidermis
Stem cell behavior varies with stimuli, and lineage changes can happen without affecting stem cell division.
research Tcf3 and Lef1 Regulate Lineage Differentiation of Multipotent Stem Cells in Skin
Tcf3 and Lef1 are key in deciding skin stem cell roles.
research Metabolic And Cellular Analysis Of Alopecia In Vitamin D Receptor Knockout Mice
Alopecia in these mice is caused by defective hair cycle communication due to missing vitamin D receptor function, not vitamin D levels.
research C-Myc Activation in Transgenic Mouse Epidermis Results in Mobilization of Stem Cells and Differentiation of Their Progeny
c-Myc activation in mouse skin increases sebaceous gland growth and affects hair follicle development.
research Multiple Roles for Activated LEF/TCF Transcription Complexes During Hair Follicle Development and Differentiation
Activated LEF/TCF complexes are crucial for hair development and cycling.
research Reversible Activation of c-Myc in Skin
Activating c-Myc in skin causes rapid cell growth and changes, but these effects are reversible.