Review of oral minoxidil as treatment of hair disorders: in search of the perfect dose
March 2021
TLDR Oral minoxidil effectively treats hair loss, with women needing lower doses (0.25 to 2.5 mg daily) and men needing higher doses (1.25 to 5 mg daily).
The review article discusses the use of oral minoxidil as a treatment for various hair disorders, including androgenetic alopecia, telogen effluvium, tractional alopecia, and others. The authors concluded that oral minoxidil is a successful and well-tolerated treatment for hair loss, with dosages varying from 0.25 to 5 mg daily. Women typically require lower doses (0.25 to 2.5 mg daily), while men require higher doses (1.25 to 5 mg daily) for maximal efficacy. The largest study cited involved 18,918 male patients with androgenetic alopecia, who showed significant improvement with a combination treatment including oral minoxidil. However, the authors recommend larger randomized comparative studies to clarify the best treatment protocol, including dosage and treatment duration.
View this study on onlinelibrary.wiley.com →
Cited in this study
research Oral minoxidil treatment for hair loss: A review of efficacy and safety
Oral minoxidil promotes hair growth but may cause side effects; needs monitoring.
research Efficacy and safety of oral minoxidil in female androgenetic alopecia
Oral minoxidil improves hair density in women with androgenetic alopecia, with mild side effects.
research Efficacy and Safety of Oral Minoxidil 5 mg Once Daily in the Treatment of Male Patients with Androgenetic Alopecia: An Open-Label and Global Photographic Assessment
Oral minoxidil 5 mg daily increases hair growth safely in men with hair loss, with minor side effects.
research Safety of low‐dose oral minoxidil treatment for hair loss. A systematic review and pooled‐analysis of individual patient data
Low-dose oral minoxidil is a safe treatment for hair loss, with the main side effect being excessive hair growth. Other side effects like foot swelling, low blood pressure when standing, and heart rate changes are rare.
research Low‐dose oral minoxidil as treatment for non‐scarring alopecia: a systematic review
Low-dose oral minoxidil effectively treats non-scarring hair loss with some side effects like hypertrichosis and postural hypotension.
research Efficacy and safety of very-low-dose oral minoxidil 1.25 mg in male androgenetic alopecia
Low-dose oral minoxidil improves hair growth in male hair loss.
research Low-Dose Oral Minoxidil for Female Pattern Hair Loss: A Unicenter Descriptive Study of 148 Women
Low-dose oral minoxidil effectively treats female hair loss with good safety.
research Oral Minoxidil: A Possible New Therapy for Androgenetic Alopecia
Oral minoxidil may improve hair loss in men and women, but has some side effects.
research Minoxidil 1 mg oral versus minoxidil 5% topical solution for the treatment of female-pattern hair loss: A randomized clinical trial
Oral minoxidil and topical minoxidil 5% both effectively improve female-pattern hair loss with safe side effects.
research Very-low-dose oral minoxidil in male androgenetic alopecia: A study with quantitative trichoscopic documentation
Low-dose oral minoxidil improved or stabilized hair loss in some patients, but higher doses may be needed for significant effects.
research Minoxidil and its use in hair disorders: a review
Minoxidil effectively treats hair loss, but use cautiously and monitor side effects.
research Effectiveness and safety of low-dose oral minoxidil in male androgenetic alopecia
Low-dose oral minoxidil effectively improves male hair loss with mild side effects.
research Case series of oral minoxidil for androgenetic and traction alopecia: Tolerability & the five C’s of oral therapy
Oral minoxidil helps hair growth, is cost-effective, and mostly well-tolerated.
research Loose anagen hair syndrome: Treatment with systemic minoxidil characterised by marked hair colour change
Minoxidil treatment can reduce hair shedding, increase hair volume, and even change hair color in patients with loose anagen hair syndrome.
research Female pattern hair loss: a pilot study investigating combination therapy with low-dose oral minoxidil and spironolactone
Low-dose oral minoxidil and spironolactone combo effectively reduces hair loss and improves hair density in women.
research Familial frontal fibrosing alopecia treated with dutasteride, minoxidil and artificial hair transplantation
Treatment with dutasteride, minoxidil, and artificial hair transplantation improved appearance but caused folliculitis.
research Treatment of permanent chemotherapy-induced alopecia with low dose oral minoxidil
Low dose oral minoxidil helps regrow hair in permanent chemotherapy-induced alopecia.
research Treatment of monilethrix with oral minoxidil
Oral minoxidil shows promise in treating monilethrix-related hair loss.
research Evaluation of Oral Minoxidil in the Treatment of Alopecia Areata
Oral minoxidil helps hair regrowth in 80% of alopecia patients, but only 18% see cosmetic improvement.
research Minoxidil: a review of its pharmacological properties and therapeutic use.
Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.
Related
research A Survey of Patient Attitudes Towards Topical Minoxidil in the Treatment of Hair Loss
Patients generally have positive attitudes towards using topical Minoxidil for hair loss treatment.
research Baricitinib Results in Eyebrow and Eyelash Growth in Patients With Alopecia Areata Who Do Not Achieve 20% or Less Scalp Hair Loss
Baricitinib helps grow eyebrows and eyelashes in severe alopecia areata patients.
research Hair loss in adult females: A clinical and trichoscopic study
Most adult women experiencing hair loss are aged 21-40, with the most common type being female pattern hair loss. Trichoscopy is a useful tool for diagnosing different types of hair loss.
research 대학병원 피부과 외래에 내원한 안드로겐 및 원형탈모증 환자에서의 대표적 Trichoscopic Finding에 대한 고찰
The document's conclusion cannot be summarized as it is not provided in a language I can understand.
research Role of Trichoscopy in Children's Scalp and Hair Disorders
Trichoscopy is good for diagnosing and monitoring hair and scalp problems in children but needs more research for certain conditions.
research Disorders of Hair
The document's conclusion cannot be provided because the document is not readable or understandable.
research Disorders of Hair
The document's conclusion cannot be provided because the document is not readable or understandable.