Review of oral minoxidil as treatment of hair disorders: in search of the perfect dose

    March 2021
    Alberto Villani, Gabriella Fabbrocini, Jorge Ocampo-Candiani, Antonio Ruggiero, Jorge Ocampo-Candiani
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    TLDR Oral minoxidil effectively treats hair loss, with women needing lower doses (0.25 to 2.5 mg daily) and men needing higher doses (1.25 to 5 mg daily).
    The review article discusses the use of oral minoxidil as a treatment for various hair disorders, including androgenetic alopecia, telogen effluvium, tractional alopecia, and others. The authors concluded that oral minoxidil is a successful and well-tolerated treatment for hair loss, with dosages varying from 0.25 to 5 mg daily. Women typically require lower doses (0.25 to 2.5 mg daily), while men require higher doses (1.25 to 5 mg daily) for maximal efficacy. The largest study cited involved 18,918 male patients with androgenetic alopecia, who showed significant improvement with a combination treatment including oral minoxidil. However, the authors recommend larger randomized comparative studies to clarify the best treatment protocol, including dosage and treatment duration.
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