Unraveling the Role of Repurposed Drugs in the Treatment of Acne: Success So Far and the Road Ahead

    February 2025 in “ Drug Development Research ”
    Popat Kumbhar, Vikas Kamble, Kaustubh Ajit Kolekar, Sukriti Vishwas, Pranav Kumbhar, Kalpana S. Patil, Gaurav Gupta, Pankaj M. Kharabe, Manisha Singh, Shailendra Gurav, Dinesh Kumar Chellappan, Sachin Kumar Singh, Kamal Dua, John Disouza, Vandana Patravale
    TLDR Repurposed drugs offer a promising, safe, and effective acne treatment.
    Repurposing existing drugs with excellent safety profiles offers a promising approach to treating acne, which affects 9.4% of the global population. Traditional treatments like antibiotics and corticosteroids have limitations, including potential skin cancer risks and microbial resistance. Repurposed drugs and phytoceuticals have shown effectiveness by targeting various signaling pathways and have demonstrated safety and efficacy in clinical trials. Despite challenges such as regulatory guidelines and clinical validation, drug repurposing is a viable strategy that could provide effective and cost-efficient acne treatment.
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