research Drug Repurposing for Rare Diseases
This review discusses drug repurposing strategies for rare diseases, highlighting methodologies, achievements, and challenges, but reports no new clinical results.
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5 / 1000+ resultsresearch Drug repurposing: A novel strategy to target cancer stem cells and therapeutic resistance
This study discusses a hypothesis for repurposing non-cancer drugs and combining micronutrients to target cancer and cancer stem cells with fewer side effects, suggesting a potential new approach for more effective cancer therapy.
research Drug Repurposing - Hypothesis, Molecular Aspects and Therapeutic Applications
The authors describe drug repurposing as a promising strategy for finding new uses for existing drugs, noting it is efficient, cost-effective, and poses lower risks than traditional drug discovery processes, potentially aiding in the treatment of rare and difficult-to-treat diseases.
research How drug repurposing can advance drug discovery: challenges and opportunities
In this article, the authors describe how drug repurposing, supported by large-scale data and artificial intelligence, can make drug discovery more cost-effective and expedient compared to traditional methods, despite certain regulatory challenges.
research Drug repurposing: Clinical practices and regulatory pathways
This article discusses drug repurposing as a strategy to find new uses for existing medications, highlighting its potential benefits like faster development and lower costs, while also addressing challenges such as drug specificity, ethical concerns, and regulatory issues.
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5 / 1000+ resultscommunity New warning by FDA on topical finasteride
The FDA warned that topical finasteride can cause serious side effects like sexual dysfunction and brain fog, similar to oral finasteride. Compounded topical formulations pose additional risks due to lack of regulation.
community Hair loss research is a money grab
Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.
community DHT is NOT very important for adults, is it?
A user experienced negative side effects, including low libido and lack of motivation, after using finasteride for hair loss and felt better after stopping it. Others shared similar experiences with finasteride and dutasteride, while some reported no side effects, showing varied individual responses.
community If you rank hairloss treatments fin,min,dut are the top 3, what's next?
Dutasteride, finasteride, and minoxidil are considered the top hair loss treatments. Other suggested treatments include Nizoral shampoo, tretinoin, pyrilutamide, zinc, biotin, and low light laser therapy, though opinions on their effectiveness vary.
community Eirion Therapeutics Announces Potential Breakthrough Treatment for Hair Loss Based on First-in-Man Clinical Trial Results
ET-02, a new hair loss treatment, shows promising results with a 6-fold increase in hair count, potentially outperforming minoxidil by activating stem cells in hair follicles. Further trials are ongoing to confirm its efficacy and safety, with potential market release in the future.
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2 / 800 results- Baricitinib: How did a drug for arthritis end up helping people regrow hair from alopecia areata? Baricitinib, an arthritis drug, was FDA-approved in 2022 for adults with severe alopecia areata after trials in which about a third of patients on 4 mg regained most scalp hair. It carries an FDA boxed warning, and regrowth is usually lost when it is stopped.
learn Minoxidil
Vasodilator used on the scalp and, at low doses, as a tablet
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