Regenerative Medicine and Hair Loss: Microneedling—Is the Pain Really Worth It?

January 2021 in “ Hair transplant forum international ”

Gorana Kuka-Epstein

microneedling hair loss hair growth combination therapies

TLDR Microneedling may help hair growth, but its pain and mixed results make its effectiveness unclear.

The article discussed the use of microneedling as a treatment for hair loss, examining its mechanism of action, indications, devices, depth, procedure, results, and combination with other therapies. The conclusion indicated that while microneedling showed promise in promoting hair growth, the pain associated with the procedure and the variability in results raised questions about its overall efficacy and patient satisfaction. The study suggested that further research was needed to optimize the technique and better understand its benefits and limitations.

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Research cited in this study

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research Preliminary Results of the Use of Scalp Microneedling in Different Types of Alopecia

24 citations, June 2019 in “Journal of Cosmetic Dermatology”

Scalp microneedling may improve hair density and thickness for various alopecia types.

research The Role of Photobiomodulation When Associated with Microneedling in Female Pattern Hair Loss

7 citations, March 2019 in “Medicine”

Combining light therapy and microneedling shows promise for treating female hair loss.

research Microneedling for the Treatment of Hair Loss

58 citations, December 2017 in “Journal of The European Academy of Dermatology and Venereology”

Microneedling can help stimulate hair growth, especially when used with other treatments, but it's not better than existing therapies.

research Repeated Microneedle Stimulation Induces Enhanced Hair Growth in a Murine Model

55 citations, January 2016 in “Annals of Dermatology”

Microneedle stimulation can increase hair growth in mice.

research Platelet-Rich Plasma Microneedling Versus 5% Topical Minoxidil in the Treatment of Patterned Hair Loss

13 citations, January 2016 in “Journal of the Egyptian Women's Dermatologic Society (Print)”

Minoxidil works faster and is more cost-effective for treating hair loss, but platelet-rich plasma microneedling can be an alternative for those who can't use minoxidil.

research Response to Microneedling Treatment in Men with Androgenetic Alopecia Who Failed to Respond to Conventional Therapy

68 citations, January 2015 in “Indian Journal of Dermatology”

Microneedling can effectively promote new hair growth in men with hair loss who didn't improve with traditional treatments.

research Epigenetic Control of Skin and Hair Regeneration After Wounding

36 citations, July 2014 in “Experimental Dermatology”

Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.

research Alopecia Areata: Successful Outcome with Microneedling and Triamcinolone Acetonide

53 citations, January 2014 in “Journal of Cutaneous and Aesthetic Surgery”

Microneedling combined with triamcinolone can safely stimulate faster hair regrowth in people with Alopecia Areata.

research Fgf9 From Dermal γδ T Cells Induces Hair Follicle Neogenesis After Wounding

237 citations, June 2013 in “Nature Medicine”

A protein from certain immune cells is key for new hair growth after skin injury in mice.

research A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study

136 citations, January 2013 in “International Journal of Trichology”

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research Microneedling and Platelet-Rich Plasma (PRP)

1 citations, March 2021

Using microneedling with PRP improves skin and hair conditions more than microneedling alone.

research Platelet Rich Plasma Combination Therapies for Treatment of Androgenetic Alopecia: A Systematic Review

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Combining platelet-rich plasma with other treatments may improve hair growth in people with hair loss, but more research is needed.

research Androgenetic Alopecia: An Update

July 2023 in “JAAD International”

Two drugs, finasteride and minoxidil, are approved for hair loss treatment, but new therapies are being developed.

research Application of Non-Pharmacologic Therapy in Hair Loss Treatment and Hair Regrowth

July 2024 in “Clinical Cosmetic and Investigational Dermatology”

Non-drug therapies show promise for hair regrowth but need more research.

Efficacy and Safety of Combinational Therapy Using Topical Minoxidil and Microneedling for the Treatment of Androgenetic Alopecia: A Systematic Review and Meta-Analysis

research Efficacy and Safety of Combinational Therapy Using Topical Minoxidil and Microneedling for the Treatment of Androgenetic Alopecia: A Systematic Review and Meta-Analysis

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Using minoxidil with microneedling increases hair count for hair loss without serious side effects.

research Microneedling and Its Use in Hair Loss Disorders: A Systematic Review

2 citations, December 2021 in “Dermatology and therapy”

Microneedling helps with hair loss, especially with 5% minoxidil, but more high-quality research is needed.