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    Smad7-Induced Beta-Catenin Degradation Alters Epidermal Appendage Development

    September 2006 in “ Developmental Cell ”
    Gangwen Han, Allen G. Li, Yao-Yun Liang … Xiaojing Wang
    Studysummary This study found that Smad7 perturbs hair follicle development while promoting sebaceous gland formation by antagonizing Wnt/β-catenin signaling in transgenic mice.
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    Research cited in this study 7

    1. Defining the Impact of Beta-Catenin/Tcf Transactivation on Epithelial Stem Cells Genes & development · 2005
    2. Defining BMP Functions in the Hair Follicle by Conditional Ablation of BMP Receptor IA The Journal of Cell Biology · 2003
    3. Hair Follicle Stem Cells: Insights from the 2003 Workshop ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2003
    4. Overexpression of Smad7 Results in Severe Pathological Alterations in Multiple Epithelial Tissues The EMBO Journal · 2002
    5. C-Myc Activation in Transgenic Mouse Epidermis Results in Mobilization of Stem Cells and Differentiation of Their Progeny Current Biology · 2001
    6. Principles of Hair Cycle Control The Journal of Dermatology · 1998
    7. Cultivation of Murine Hair Follicles as Organoids in a Collagen Matrix Journal of Investigative Dermatology · 1987