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    Case Report of a Patient With Psoriasis Vulgaris, Psoriatic Arthritis, and Alopecia Universalis Successfully Treated With Tofacitinib and Methotrexate

    May 2025 in “ JEADV Clinical Practice ”
    Jan Nicolai Wagner, Matthias Augustin, Caroline Gewiss … Nesrine Ben‐Anaya
    Studysummary This case study reports significant improvements in joint pain and hair regrowth in a 31-year-old female with alopecia universalis, psoriasis vulgaris, and psoriatic arthritis using a combination of tofacitinib and methotrexate after other treatments failed.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 9

    1. Drug Survival and Long-Term Outcome of Tofacitinib in Patients with Alopecia Areata: A Retrospective Study Acta dermato-venereologica · 2023
    2. Effectiveness of Oral Tofacitinib Treatment on Patients With Moderate-to-Severe Alopecia Areata in Iran Journal of Cosmetic Dermatology · 2023
    3. Epidemiology of Alopecia Areata and Population-Wide Comorbidities in Germany: Analysis of Longitudinal Claims Data British journal of dermatology/British journal of dermatology, Supplement · 2023
    4. Novel Potential Therapeutic Targets of Alopecia Areata Frontiers in Immunology · 2023
    5. Two Phase 3 Trials of Baricitinib for Alopecia Areata The New England Journal of Medicine · 2022
    6. Oral Tofacitinib for the Treatment of Alopecia Areata in Pediatric Patients Pediatric Dermatology · 2021
    7. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    8. JAK Inhibitors for Alopecia Areata: A Systematic Review and Meta-Analysis JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2019
    9. Killing Two Birds with One Stone: Oral Tofacitinib Reverses Alopecia Universalis in a Patient with Plaque Psoriasis Journal of Investigative Dermatology · 2014

    Related research 6

    1. Alopecia Universalis Treated With Tofacitinib: The Role of JAK/STAT Inhibitors in Hair Regrowth Cutis · 2023
    2. The Usefulness and Wellbeing of Tofacitinib in the Treatment of Alopecia Areata Journal of Armed Forces Medical College, Bangladesh · 2022
    3. Successful Treatment of Severe Alopecia Areata With Oral or Topical Tofacitinib PubMed · 2018
    4. Brazilian Experience of Treating Alopecia Universalis with Novel Antirheumatic Therapy Tofacitinib: A Case Series Rheumatology and Therapy · 2017
    5. Excellent Response to Tofacitinib Treatment in a Patient with Alopecia Universalis Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.) · 2017
    6. Alopecia Areata Universalis in a Dog Veterinary dermatology · 2015