Platelet Rich Plasma Use for Treatment of Acne Scars: An Overview of Systematic Reviews

May 2024 in “ PubMed ”

Mario Cruciani, Francesca Masiello, Ilaria Pati, Simonetta Pupella, Vincenzo De Angelis

platelet-rich plasma microneedling laser therapy acne scars PRP

From the encyclopedia

growth factors taken from your blood and injected into your scalp to stimulate hair

technique to create small wounds in skin to activate collagen production and hair growth

Studysummary This study found that the current evidence is of low or very low certainty and thus does not clearly support using PRP in combination with microneedling or laser therapy for treating acne scars, indicating a need for further well-designed studies.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The document concludes that the current evidence supporting the use of platelet-rich plasma (PRP) in combination with microneedling or laser therapy for treating acne scars is of low or very low certainty. This lack of strong evidence makes it difficult to make clear clinical decisions regarding the effectiveness of PRP combination therapy for acne scars. The document emphasizes the need for further well-designed studies to enhance the evidence base in this area.

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Research cited in this study

8 / 8 results

research Platelet-Rich Plasma for the Treatment of Alopecia: A Systematic Review and Meta-Analysis

1 citations , January 2023 in “PubMed”

This systematic review and meta-analysis found limited, low-quality evidence suggesting that platelet-rich plasma injections may increase hair density in patients with androgenetic alopecia compared to saline, but results were inconclusive for alopecia areata.

research A Comprehensive Review of Platelet-Rich Plasma for the Treatment of Dermatologic Disorders

1 citations , November 2022 in “Journal of Dermatological Treatment”

This review discusses the use of platelet-rich plasma for various dermatologic conditions but reports inconsistent evidence and a lack of standardized protocols; patients often report high satisfaction despite mixed clinical outcomes.

research Combined Effect of Microneedling and Platelet-Rich Plasma for the Treatment of Acne Scars: A Meta-Analysis

7 citations , February 2022 in “Frontiers in Medicine”

This study found that combining microneedling with PRP was more effective than microneedling alone for improving acne scars, with higher patient satisfaction and no significant increase in severe side effects.

research Comment on 'Platelet-Rich Plasma and Its Utility in the Treatment of Acne Scars: A Systematic Review'

4 citations , September 2019 in “Journal of The American Academy of Dermatology”

This study found that combining platelet-rich plasma with microneedling or fractional CO2 laser therapy was more effective in treating postacne atrophic scars than using these therapies alone, also boosting patient satisfaction.

research A Meta-Analysis of the Evidence for Assisted Therapy with Platelet-Rich Plasma for Atrophic Acne Scars

16 citations , September 2019 in “Aesthetic Plastic Surgery”

Platelet-rich plasma therapy helps improve atrophic acne scars.

research The Efficacy of Platelet-Rich Plasma in Hair Restoration and Facial Aesthetics: A Systematic Review and Meta-Analysis

31 citations , January 2019 in “Journal of Cutaneous Medicine and Surgery”

This review found that three monthly PRP injections improved hair density in patients with androgenetic alopecia compared to placebo, but more rigorous studies are needed for broader dermatological applications.

research Evaluating Platelet-Rich Plasma Therapy for Facial Aesthetics and Alopecia

31 citations , April 2018 in “Plastic and Reconstructive Surgery”

This review discusses the use of platelet-rich plasma for facial rejuvenation, acne scarring, and androgenic alopecia and reports positive outcomes but emphasizes the need for standardized preparation and application methods.

research Systematic Review of the Use of Platelet-Rich Plasma in Aesthetic Dermatology

113 citations , July 2015 in “Journal of Cosmetic Dermatology”

This review discusses the cosmetic applications of platelet-rich plasma in dermatology, highlighting its potential benefits and the need for more controlled studies.