Integrating Proteomics Revealed Key Targets for Molecular Breeding of Fine Cashmere Traits in Cashmere Goats

    October 2025 in “ Frontiers in Veterinary Science ”
    Chongyan Zhang, Yichuan Wang, Anru Xing … Zhihong Liu
    Studysummary This study found that the finer fibers of Alpas cashmere, compared to ordinary cashmere, are associated with the down-regulation of specific keratins and keratin-associated proteins, suggesting a molecular target for breeding cashmere goats with improved fiber quality.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on frontiersin.org →
    Discuss this study in the Community →

    Research cited in this study 8

    1. Deciphering the Molecular Drivers for Cashmere/Pashmina Fiber Production in Goats: A Comprehensive Review Mammalian Genome · 2025
    2. Melatonin Promotes Cashmere Goat (Capra Hircus) Secondary Hair Follicle Growth: A View from Integrated Analysis of Long Non-Coding and Coding RNAs Cell Cycle · 2018
    3. Integrative Analysis Reveals ncRNA-Mediated Molecular Regulatory Network Driving Secondary Hair Follicle Regression in Cashmere Goats BMC Genomics · 2018
    4. Identification of Genes and Proteins Associated with Anagen Wool Growth Animal genetics · 2016
    5. Mammalian Keratin-Associated Proteins (KRTAPs) Subgenomes: Disentangling Hair Diversity and Adaptation to Terrestrial and Aquatic Environments BMC genomics · 2014
    6. Aging Processes Influence Keratin and KAP Expression in Human Hair Follicles Experimental Dermatology · 2011
    7. Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin Nature Reviews Molecular Cell Biology · 2009
    8. An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation Proceedings of the National Academy of Sciences of the United States of America · 1996