Evolution and Mechanistic Insights of Platelet-Derived Products in Temporomandibular Joint Regeneration

January 2026 in “ Frontiers in Cell and Developmental Biology ”

Cong Lin, Yutong Jin, Dan Li, Qiaoli Yang, T.S. Chen, Q. L. CHEN, Mei Zhang, Zhangbiao Long, Dongdong Fang

platelet-rich plasma platelet-rich fibrin autologous platelet-derived products mesenchymal stem cell proliferation chondrogenic differentiation immunomodulatory pathways temporomandibular joint temporomandibular disorders PRP APDs TMJ TMDs

Studysummary This review discusses the molecular mechanisms and clinical applications of autologous platelet-derived products for TMJ regeneration, but reports no new clinical results.

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