Enhancing Pain Relief in Temporomandibular Joint Arthrocentesis: Platelet-Rich Plasma and Hyaluronic Acid Synergy

This review examines the synergistic use of platelet-rich plasma (PRP) and hyaluronic acid (HA) in temporomandibular joint (TMJ) arthrocentesis, highlighting their combined benefits for pain relief and functional improvement. PRP's regenerative and anti-inflammatory properties, along with HA's lubricating effects, offer a comprehensive approach to managing TMJ disorders. Clinical studies show significant pain reduction and improved mobility with this therapy, which is generally safe with mild, transient adverse effects. However, more extensive randomized controlled trials are needed to confirm long-term efficacy and safety. The combination of PRP and HA presents a promising pathway for enhancing patient outcomes in TMJ disorder management.