Palatogenesis and cutaneous repair: A two‐headed coin

    November 2014 in “ Developmental Dynamics
    Leah C. Biggs, Steven L. Goudy, Martine Dunnwald
    TLDR Palate formation and skin healing share similar biological processes.
    The document reviewed the similarities between palatogenesis, the formation of the palate during embryogenesis, and the process of cutaneous wound healing. Both processes involve cellular proliferation, migration, differentiation, and fusion, which are essential for closing gaps, whether in developing tissues or healing skin. The review highlighted that orofacial clefting and wound healing share conserved pathways and gene regulatory networks, suggesting a fundamental connection between developmental processes and post-natal tissue repair mechanisms.
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