Topical Administration of 15-Deoxy-Δ12,14-Prostaglandin J2 Using a Nonionic Cream: Effect on UVB-Induced Skin Oxidative, Inflammatory, and Histopathological Modifications in Mice

    January 2021 in “ Mediators of Inflammation ”
    Clovis M. Kumagai, Renata M. Martínez, Bárbara B. Colombo, Priscila Saito, Ingrid C. Pinto, Camilla C. A. Rodrigues, David L. Vale, Ricardo Luís Nascimento de Matos, Ana Paula Frederico Rodrigues Loureiro Bracarense, Marcela M. Baracat, Sandra R. Georgetti, Juliana Trindade Clemente‐Napimoga, Marcelo Henrique Napimoga, Victor Fattori, Waldiceu A. Verri, Rúbia Casagrande
    Studysummary In this study, 15d-PGJ2 administered in a topical cream inhibited oxidative and inflammatory skin changes caused by UVB radiation in hairless mice, suggesting it as a promising treatment approach.
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