Preparation of 4-Aryl-2-Trifluoromethylbenzonitrile Derivatives as Androgen Receptor Antagonists for Topical Suppression of Sebum Production

    August 2007 in “ Bioorganic & Medicinal Chemistry Letters ”
    Jennifer A. Van Camp, Lain-Yen Hu, Catherine R. Kostlan … Kimberly Jane Wade
    Studysummary This study found that among the tested analogs, compound 4e was the most effective in inhibiting wax esters in vivo in the Golden Syrian hamster ear model.
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    Research cited in this study 1

    1. Cutaneous Androgen Metabolism: Basic Research And Clinical Perspectives ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002

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