Post-Finasteride Syndrome

    August 2019 in “ BMJ ”
    Shelly L. Gray, Todd P. Semla
    Studysummary This article reviews ongoing concerns about the safety of 5α-reductase inhibitors like finasteride, highlighting the lack of long-term data on persistent depression and sexual side effects after drug discontinuation; no new clinical results are reported.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 10

    1. Incidence of Type 2 Diabetes Mellitus in Men Receiving Steroid 5α-Reductase Inhibitors: Population-Based Cohort Study BMJ. British medical journal · 2019
    2. A Review of the FAERS Data on 5-Alpha Reductase Inhibitors: Implications for Postfinasteride Syndrome Urology · 2018
    3. Association of Suicidality and Depression With 5α-Reductase Inhibitors JAMA Internal Medicine · 2017
    4. Persistent Erectile Dysfunction in Men Exposed to 5α-Reductase Inhibitors, Finasteride, or Dutasteride PeerJ · 2017
    5. Risk of Erectile Dysfunction Associated with Use of 5-Alpha Reductase Inhibitors for Benign Prostatic Hyperplasia or Alopecia: Population-Based Studies Using the Clinical Practice Research Datalink BMJ · 2016
    6. Investigation of the Plausibility of 5-Alpha-Reductase Inhibitor Syndrome Skin appendage disorders · 2016
    7. Adverse Event Reporting in Clinical Trials of Finasteride for Androgenic Alopecia: A Meta-Analysis PubMed · 2015
    8. Persistent Sexual Side Effects of Finasteride: Could They Be Permanent? The Journal of Sexual Medicine · 2012
    9. Persistent Sexual Side Effects of Finasteride for Male Pattern Hair Loss The Journal of Sexual Medicine · 2011
    10. Finasteride 5mg and Sexual Side Effects: How Many Are Related to a Nocebo Phenomenon? The Journal of Sexual Medicine · 2007

    Related research 2

    1. Similar Efficacy of Maintenance Treatment of Finasteride 1 mg Every Other Month Compared with Finasteride 1 mg Daily in Korean Men with Androgenetic Alopecia After Taking Finasteride 1 mg Daily for 1 Year Journal of The American Academy of Dermatology · 2020
    2. Use of Finasteride in the Treatment of Men With Androgenetic Alopecia Journal of Investigative Dermatology Symposium Proceedings · 2003