Concise Review: Translating Regenerative Biology Into Clinically Relevant Therapies: Are We on the Right Path?

    December 2017 in “ Stem Cells Translational Medicine ”
    Jennifer Simkin, Ashley W. Seifert
    Studysummary This review discusses how studying regenerative biology in certain mammalian models could enhance our understanding of complex tissue regeneration, but it reports no new clinical findings.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 7

    1. The Blastema and Epimorphic Regeneration in Mammals Developmental Biology · 2017
    2. The Periosteal Requirement and Temporal Dynamics of BMP2-Induced Middle Phalanx Regeneration in the Adult Mouse Regeneration · 2017
    3. Regeneration of Fat Cells from Myofibroblasts During Wound Healing Science · 2017
    4. Inhibition of β-Catenin Signaling in Dermal Fibroblasts Enhances Hair Follicle Regeneration During Wound Healing Development · 2016
    5. Distinct Fibroblast Lineages Determine Dermal Architecture in Skin Development and Repair Nature · 2013
    6. Skin Shedding and Tissue Regeneration in African Spiny Mice (Acomys) Nature · 2012
    7. Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin Nature Reviews Molecular Cell Biology · 2009