Neurosteroids And Epileptogenesis
June 2013
in “
Journal of Neuroendocrinology
”
Research cited in this study
6 / 6 resultsresearch Temporal Lobe Epilepsy Exacerbation During Pharmacological Inhibition of Endogenous Neurosteroid Synthesis
Stopping finasteride improved seizure control, suggesting neurosteroids affect seizures and treatment.
research Neurosteroids And Epileptogenesis In The Pilocarpine Model: Evidence For A Relationship Between P450scc Induction And Length Of The Latent Period
research Studies on Neurosteroids XXV: Influence of a 5α-Reductase Inhibitor, Finasteride, on Rat Brain Neurosteroid Levels and Metabolism
Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.
research Endogenous Neurosteroids Modulate Epileptogenesis in a Model of Temporal Lobe Epilepsy
research Anticonvulsant Activity of Progesterone and Neurosteroids in Progesterone Receptor Knockout Mice
research Finasteride, a 5alpha-Reductase Inhibitor, Blocks the Anticonvulsant Activity of Progesterone in Mice
Finasteride, a drug, can block the seizure-preventing effects of a hormone called progesterone in mice.
Related Research
1 / 1 results
research Finasteride Inhibits the Disease-Modifying Activity of Progesterone in the Hippocampus Kindling Model of Epileptogenesis
Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.