Neurosteroids And Epileptogenesis In The Pilocarpine Model: Evidence For A Relationship Between P450scc Induction And Length Of The Latent Period
January 2009
in “
Epilepsia
”
Studysummary In this study, status epilepticus in rats induced P450scc in hippocampal glia, which was associated with a delayed onset of spontaneous seizures, while inhibiting neurosteroid synthesis accelerated seizure onset if P450scc was significantly increased.
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