March 2026 in “Critical Care Medicine” This study reports a rare case of refractory status epilepticus in a 48-year-old man after a hair transplant, likely due to neurotoxic effects from combined use of local anesthetics and tranexamic acid, highlighting the importance of early recognition and management of such complications.
62 citations
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January 2009 in “Epilepsia” In this study, status epilepticus in rats induced P450scc in hippocampal glia, which was associated with a delayed onset of spontaneous seizures, while inhibiting neurosteroid synthesis accelerated seizure onset if P450scc was significantly increased.
14 citations
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December 2017 in “Journal of Intensive Care” Lithium poisoning can cause severe health complications and requires careful monitoring.
March 2023 in “Epilepsia” This study suggests that repeated trilostane treatment increases brain allopregnanolone levels and delays epileptogenesis in rats after status epilepticus.
20 citations
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January 2017 in “Epilepsia” In this study, inhibition of neurosteroid synthesis after inducing status epilepticus in rats led to acute seizures and accelerated the onset of epilepsy, suggesting a role for δ-GABAR plasticity in epileptogenesis.