The Investigation of Minoxidil-Induced Ca2+ Rises and Non-Ca2+-Triggered Cell Death in PC3 Human Prostate Cancer Cells

    I-Shu Chen, Chiang-Ting Chou, Yuan-Yuarn Liu … Chung‐Ren Jan
    Studysummary This study found that minoxidil increases cytosolic-free Ca2+ levels and induces cytotoxicity in PC3 human prostate cancer cells, with the cytotoxicity occurring in a Ca2+-independent manner.
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    Research cited in this study 8

    1. Emerging Treatments in Alopecia Expert Opinion on Emerging Drugs · 2014
    2. Minoxidil May Suppress Androgen Receptor-Related Functions Oncotarget · 2014
    3. Female Pattern Hair Loss: A Review Article international journal of endocrinology and metabolism · 2013
    4. Minoxidil Use in Dermatology, Side Effects, and Recent Patents Recent Patents on Inflammation & Allergy Drug Discovery · 2012
    5. Rapid Determination of Minoxidil in Human Plasma Using Ion-Pair HPLC Journal of Pharmaceutical and Biomedical Analysis · 2004
    6. Effect of Minoxidil Sulfate and Pinacidil on Single Potassium Channel Current in Cultured Human Outer Root Sheath Cells and Dermal Papilla Cells Journal of Dermatological Science · 1994
    7. Minoxidil: Inhibition of Proliferation of Keratinocytes In Vitro Journal of Investigative Dermatology · 1991
    8. Suppression of Fibroblast Proliferation and Lysyl Hydroxylase Activity by Minoxidil Journal of Biological Chemistry · 1987

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