First Report on Microbial-Derived Polydeoxyribonucleotide: A Sustainable and Enhanced Alternative to Salmon-Based Polydeoxyribonucleotide

    January 2025 in “ Current Issues in Molecular Biology ”
    Doobyeong Chae, Sae-Woong Oh, Yoon-Seo Choi … Won-Sang Seo
    Studysummary This study found that PDRN derived from Lactobacillus rhamnosus showed superior antioxidant and wound-healing properties compared to salmon-derived PDRN, while also offering potential benefits in immune modulation and bioavailability.
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    Research cited in this study 6

    1. Analysis of Skin Regeneration and Barrier-Improvement Efficacy of Polydeoxyribonucleotide Isolated from Panax Ginseng Adventitious Root Molecules · 2023
    2. An Effective Range of Polydeoxyribonucleotides Is Critical for Wound Healing Quality Molecular Medicine Reports · 2018
    3. Pharmacological Activity and Clinical Use of Polydeoxyribonucleotide Frontiers in Pharmacology · 2017
    4. Novel Anti-Melanogenesis Properties of Polydeoxyribonucleotide, a Popular Wound Healing Booster International Journal of Molecular Sciences · 2016
    5. The Effect of Particle Size on the Deposition of Solid Lipid Nanoparticles in Different Skin Layers: A Histological Study Advanced Pharmaceutical Bulletin · 2016
    6. Therapeutic Efficacy of Autologous Platelet-Rich Plasma and Polydeoxyribonucleotide on Female Pattern Hair Loss Wound Repair and Regeneration · 2014