The Role of Correction of Metabolic Disorders in the Treatment of Androgenetic Alopecia in Women

October 2016 in “ Rossiiskii Zhurnal Kozhnykh i Venericheskikh Boleznei ”

Yu. N. Perlamutrov, Mikhail Borisovich Antsiferov, Natalia N. Levina

androgenetic alopecia insulin resistance dyslipidemia hyperandrogenism minoxidil metformin AGA Rogaine

From the encyclopedia

Minoxidil →

An essential vasodilator with some anti-androgenic effects

Metformin →

diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

Studysummary In this study, women with androgenetic alopecia showed abnormalities in carbohydrate and lipid metabolism, and treatment with metformin improved clinical outcomes.

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Research cited in this study

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research Androgenetic Alopecia, Metabolic Syndrome, and Insulin Resistance: Is There Any Association? A Case-Control Study

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research Vellus Hairs in the Frontal Scalp in Early Female Pattern Hair Loss

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This study suggests that the presence of more than six vellus hairs in the frontal scalp at 20-fold magnification can be an additional criterion for diagnosing early female pattern hair loss.

research Hair Loss in Elderly Women: A Dermatological Concern

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This article discusses hair loss in postmenopausal women as often being multifactorial, reviewing various conditions affecting this group, but reports no new research findings.

research Female Pattern Hair Loss in Complete Androgen Insensitivity Syndrome

54 citations , February 2010 in “British Journal of Dermatology”

This case report describes a patient with complete androgen insensitivity syndrome experiencing female pattern hair loss, suggesting that factors beyond direct androgen action may contribute to this condition in women.

research The Diagnosis and Treatment of Iron Deficiency and Its Potential Relationship to Hair Loss

207 citations , April 2006 in “Journal of The American Academy of Dermatology”

This review discusses the complexities of diagnosing and treating iron deficiency related to nutritional anemia and hair loss, concluding that routine screening and supplementation for hair loss are not yet supported by sufficient evidence.

research Kenogen in Female Androgenetic Alopecia

40 citations , December 2004 in “Dermatology”

This study suggests that an increase in kenogen phases, along with rising vellus hair cycles and fewer normal hair cycles, is associated with the progression of female androgenetic alopecia.

research Current and Novel Methods for Assessing Efficacy of Hair Growth Promoters in Pattern Hair Loss

86 citations , February 2003 in “Journal of The American Academy of Dermatology”

This article discusses various mechanisms for promoting hair growth in pattern hair loss and highlights the challenge of balancing short-term measurable results in trials with the need for long-term efficacy data.

research Classification of the Types of Androgenetic Alopecia (Common Baldness) Occurring in the Female Sex

666 citations , September 1977 in “British Journal of Dermatology”

This article presents a classification system for stages of female-pattern androgenetic alopecia to aid early diagnosis and mentions existing systems for rare male-pattern cases, but reports no new clinical results.