Hirsutism Beyond PCOS: Genome-Wide Evidence for Genetic Factors

    Jasmin H. Takala, Natàlia Pujol‐Gualdo, Triin Laisk … Jaakko Tyrmi
    Studysummary In this study, genetic factors associated with hirsutism were identified, suggesting that both androgen-dependent and independent mechanisms may contribute to excessive hair growth in women.
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    Research cited in this study 12

    1. A Comprehensive Review of Genome-Wide Association Studies of Human Hair Traits Journal of Investigative Dermatology · 2025
    2. Polycystic Ovary Syndrome Nature Reviews Disease Primers · 2024
    3. Recommendations From The 2023 International Evidence-Based Guideline For The Assessment And Management Of Polycystic Ovary Syndrome Fertility and Sterility · 2023
    4. Genome-Wide Association Study in Japanese Females Identifies Fifteen Novel Skin-Related Trait Associations Scientific reports · 2018
    5. Genetic Prediction of Male Pattern Baldness PLoS Genetics · 2017
    6. Endocrine Evaluation of Hirsutism International Journal of Women's Dermatology · 2015
    7. The Focal Adhesion Protein PINCH-1 Associates With EPLIN at Integrin Adhesion Sites Journal of Cell Science · 2015
    8. FGF5 Is a Crucial Regulator of Hair Length in Humans Proceedings of the National Academy of Sciences of the United States of America · 2014
    9. Six Novel Susceptibility Loci for Early-Onset Androgenetic Alopecia and Their Unexpected Association with Common Diseases PLOS Genetics · 2012
    10. The Clinical Evaluation of Hirsutism Dermatologic therapy · 2008
    11. The Long And The Short Of It: Evidence That FGF5 Is A Major Determinant Of Canine Hair-Itability Animal genetics · 2006
    12. Hirsutism New England journal of medicine/˜The œNew England journal of medicine · 2005