Characterization of Epithelial Hair Follicle Stem Cells in Lichen Planopilaris and Folliculitis Decalvans Through Keratin 19 Expression
December 2025
in “
American Journal of Dermatopathology
”
TLDR Keratin 19 may help diagnose and treat certain types of permanent hair loss.
The study investigates the expression of Keratin 19 in epithelial hair follicle stem cells in patients with Lichen Planopilaris and Folliculitis Decalvans. These conditions are types of scarring alopecia that lead to permanent hair loss. The research aims to better understand the role of Keratin 19 as a marker for hair follicle stem cells in these diseases, potentially aiding in the development of targeted therapies. The study involved the analysis of surplus biopsy material from patients, with all participants providing informed consent. The findings could contribute to improved diagnostic and treatment strategies for these forms of alopecia.