Tofacitinib in the Management of Alopecia Universalis

    September 2023 in “ International Journal of Trichology ”
    Prashant Agarwal
    Studysummary This case report describes a successful treatment of alopecia universalis in a 37-year-old female using oral tofacitinib, along with other therapies, resulting in significant hair regrowth without notable safety concerns.
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    Research cited in this study 11

    1. Alopecia Areata: Case Report and Review of Pathophysiology and Treatment with JAK Inhibitors Journal of autoimmunity · 2022
    2. Resistant Alopecia Areata Treated with Tofacitinib International Journal of Trichology · 2022
    3. Treatment of Resistant Alopecia Areata with Tofacitinib International Journal of Trichology · 2022
    4. Alopecia Areata: An Update on Etiopathogenesis, Diagnosis, and Management Clinical Reviews in Allergy & Immunology · 2021
    5. JAK Inhibitors for Alopecia Areata: A Systematic Review and Meta-Analysis JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2019
    6. An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis Journal of Investigative Dermatology · 2018
    7. JAK Inhibitors in Dermatology: The Promise of a New Drug Class Journal of the American Academy of Dermatology · 2017
    8. Tofacitinib for the Treatment of Alopecia Areata and Variants in Adolescents Journal of the American Academy of Dermatology · 2016
    9. Tofacitinib for the Treatment of Severe Alopecia Areata and Variants: A Study of 90 Patients Journal of The American Academy of Dermatology · 2016
    10. Safety and Efficacy of the JAK Inhibitor Tofacitinib Citrate in Patients with Alopecia Areata JCI insight · 2016
    11. Topical Ruxolitinib for the Treatment of Alopecia Universalis JAMA dermatology · 2015

    Related research 7

    1. Steroid-Free Monotherapy with Tofacitinib in Severe Therapy-Resistant Alopecia: A Retrospective Analysis Indian Dermatology Online Journal · 2023
    2. Alopecia Universalis Treated With Tofacitinib: The Role of JAK/STAT Inhibitors in Hair Regrowth Cutis · 2023
    3. Alopecia Areata Flare Patterns in Children and Young Adults on Systemic Tofacitinib Journal of the American Academy of Dermatology · 2021
    4. Alopecia Universalis: Partial Response to Tofacitinib Medicina Clínica (English Edition) · 2019
    5. Brazilian Experience of Treating Alopecia Universalis with Novel Antirheumatic Therapy Tofacitinib: A Case Series Rheumatology and Therapy · 2017
    6. Alopecia Universalis Successfully Treated With Tofacitinib Journal of the American Academy of Dermatology · 2017
    7. Excellent Response to Tofacitinib Treatment in a Patient with Alopecia Universalis Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.) · 2017