Isotretinoin and Hair Loss: A Clinical Perspective and Literature Review

    Alekhya Gurram, Mary Cavanagh, Lindy Ross
    Studysummary This study reports a case of alopecia areata in a 14-year-old male using isotretinoin for acne, illustrating an unexpected side effect not typically linked to the drug, highlighting the importance of monitoring and addressing hair loss risks during treatment.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 14

    1. Psychological Stress-Induced Pathogenesis of Alopecia Areata: Autoimmune and Apoptotic Pathways International journal of molecular sciences · 2023
    2. Characteristics of Patients with Hair Loss After Isotretinoin Treatment International Journal of Trichology · 2022
    3. Adverse Events in Isotretinoin Therapy: A Single-Arm Meta-Analysis International Journal of Environmental Research and Public Health · 2022
    4. Comparing the Frequency of Isotretinoin-Induced Hair Loss at <0.5 mg/kg/d Versus ≥0.5 mg/kg/d Dosing in Acne Patients: A Systematic Review JAAD International · 2022
    5. Evaluation of Biophysical Skin Parameters and Hair Changes in Patients with Acne Vulgaris Treated with Isotretinoin, and the Effect of Biotin Use on These Parameters International Journal of Dermatology · 2021
    6. FDA Reports of Alopecia as an Adverse Event to Isotretinoin Journal of Cutaneous Medicine and Surgery · 2019
    7. The Role of Vitamins and Minerals in Hair Loss: A Review Dermatology and Therapy · 2018
    8. Effects of Isotretinoin on the Hair Cycle Journal of Cosmetic Dermatology · 2018
    9. Evaluation and Diagnosis of the Hair Loss Patient Journal of The American Academy of Dermatology · 2014
    10. Evaluation of Biophysical Skin Parameters and Assessment of Hair Growth in Patients with Acne Treated with Isotretinoin Postepy Dermatologii I Alergologii · 2013
    11. Endogenous Retinoids in the Pathogenesis of Alopecia Areata ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2012
    12. Drug Reactions Affecting Hair: Diagnosis Dermatologic Clinics · 2007
    13. Towards Dissecting the Pathogenesis of Retinoid-Induced Hair Loss: All-Trans Retinoic Acid Induces Premature Hair Follicle Regression by Upregulation of Transforming Growth Factor-β2 in the Dermal Papilla Journal of Investigative Dermatology · 2005
    14. Novel Cycle Changes in Scalp Hair Are Caused by Etretinate Therapy British Journal of Dermatology · 1995

    Related research 1

    1. Characteristics of Patients with Hair Loss After Isotretinoin Treatment International Journal of Trichology · 2022