Characteristics of Patients with Hair Loss After Isotretinoin Treatment

    July 2022 in “ International Journal of Trichology ”
    Patrick Tran, Evyatar Evron, Carolyn Goh
    TLDR Higher doses and longer use of isotretinoin may increase hair loss risk.
    This retrospective study examined the characteristics of patients who experienced hair loss after isotretinoin treatment. Out of 6,330 patients with hair loss, 48 had been prescribed isotretinoin between 2013 and 2018, and 19 of these experienced hair loss concurrently or within 2 years of treatment. The study found that patients who developed hair loss were generally older, had higher cumulative doses, and longer treatment durations compared to those who did not experience hair loss. The study suggested that dosage and duration might be linked to hair loss, although the exact mechanism remained unclear. The findings were intended to aid in counseling patients concerned about hair loss when considering isotretinoin treatment. Limitations included the small number of affected cases and the retrospective nature of the study.
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