High-Sulfur Protein Gene Expression in a Transgenic Mouse

    December 1991 in “ Annals of the New York Academy of Sciences ”
    Gabriel Vögeli, Linda S. Wood, Alistair R. McNab … Allen E. Buhl
    Studysummary This study found that minoxidil increases the expression of a reporter gene linked to hair growth in cultured hair follicles from transgenic mice, suggesting a potential model for studying hair biology.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on nyaspubs.onlinelibrary.wiley.com →
    Discuss this study in the Community →

    Research cited in this study 11

    1. Expression of Calcyclin, a Calcium-Binding Protein, in the Keratogenous Region of Growing Hair Follicles Journal of Investigative Dermatology · 1991
    2. Serine-Rich Ultra High Sulfur Protein Gene Expression in Murine Hair and Skin During the Hair Cycle Journal of Biological Chemistry · 1990
    3. Hair-Specific Expression of Chloramphenicol Acetyltransferase in Transgenic Mice Under the Control of an Ultra-High-Sulfur Keratin Promoter Proceedings of the National Academy of Sciences · 1990
    4. The cDNA-Deduced Amino Acid Sequence for Trichohyalin, a Differentiation Marker in the Hair Follicle, Contains a 23 Amino Acid Repeat ˜The œjournal of cell biology/˜The œJournal of cell biology · 1990
    5. Minoxidil Stimulates Mouse Vibrissae Follicles in Organ Culture Journal of Investigative Dermatology · 1989
    6. An Ultra-High Sulfur Keratin Gene Is Expressed Specifically During Hair Growth Journal of Investigative Dermatology · 1989
    7. A New Look Into an Old Problem: Keratins as Tools to Investigate Determination, Morphogenesis, and Differentiation in Skin Genes & Development · 1989
    8. Cloning And Characterization Of A Mouse Type I Hair Keratin cDNA Journal of Investigative Dermatology · 1988
    9. The Complement of Native Alpha-Keratin Polypeptides of Hair-Forming Cells: A Subset of Eight Polypeptides That Differ from Epithelial Cytokeratins Differentiation · 1986
    10. Trichohyalin, an Intermediate Filament-Associated Protein of the Hair Follicle ˜The œjournal of cell biology/˜The œJournal of cell biology · 1986
    11. Growth of the Hair Physiological Reviews · 1954

    Related research 9

    1. Minoxidil Sulfotransferase Enzymatical Activity in Plants: A Novel Paradigm in Increasing Minoxidil Response in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2023
    2. Tretinoin Enhances Minoxidil Response in Androgenetic Alopecia Patients by Upregulating Follicular Sulfotransferase Enzymes Dermatologic Therapy · 2019
    3. The Use of Minoxidil in the Treatment of Male and Female Androgenetic Alopecia: A Story of More Than 30 Years Italian journal of dermatology and venereology · 2018
    4. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    5. Effects of TNF-Alpha and Minoxidil on Human Hair Growth In Vitro Journal of Clinical Dermatology · 2003
    6. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    7. KF19418, A New Compound for Hair Growth Promotion in Vitro and in Vivo Mouse Models Journal of Dermatological Science · 2001
    8. Effect of Minoxidil on Cultured Human Hair Follicle Cells Journal of Dermatological Science · 1990
    9. Sulfation of Minoxidil in Keratinocytes and Hair Follicles PubMed · 1989