Imbalance of T-Helper 17 and Regulatory T Cells in Patients with Alopecia Areata

    June 2015 in “ The Journal of Dermatology ”
    Yong Han, Yuan Sheng, Feng Xu … Qinping Yang
    Studysummary This study found that patients with alopecia areata had higher levels of Th17 cells and lower levels of regulatory T cells compared to healthy controls, suggesting an immune imbalance in these patients.
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    Research cited in this study 5

    1. Histopathology of Alopecia Areata, Acute and Chronic: Why Is It Important to the Clinician? Dermatologic Therapy · 2011
    2. Current Standards in the Diagnostics and Therapy of Hair Diseases - Hair Consultation Journal der Deutschen Dermatologischen Gesellschaft · 2011
    3. Quality of Life in Alopecia Areata: A Study of 60 Cases Journal of Investigative Dermatology · 2010
    4. Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity Nature · 2010
    5. Transient CD44 Variant Isoform Expression and Reduction in CD4+/CD25+ Regulatory T Cells in C3H/HeJ Mice with Alopecia Areata Journal of Investigative Dermatology · 2002

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