Genetic Prediction Of Male Pattern Baldness

    August 2016 in “ bioRxiv (Cold Spring Harbor Laboratory) ”
    Saskia P. Hagenaars, W. David Hill, Sarah E. Harris, Stuart J. Ritchie, Gail Davies, David C. Liewald, Catharine R. Galé, David J. Porteous, Ian J. Deary, Riccardo E. Marioni
    TLDR Genetic factors can predict male pattern baldness risk.
    The study investigated the genetic basis of male pattern baldness using data from over 52,000 male participants in the UK Biobank, aged 40-69 years. Researchers identified more than 250 novel genetic loci associated with severe hair loss. They developed a prediction algorithm based on common genetic variants, which accurately distinguished between individuals with no hair loss and those with severe hair loss (AUC = 0.82). These findings could help identify individuals at high risk for hair loss and suggest potential genetic targets for intervention.
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      in Chat  225 upvotes 4 months ago
      Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

      community Genetics are so weird and unpredictable

      in Minoxidil  118 upvotes 1 year ago
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