Identification of Genes Influencing Formation of the Type III Brush Hair in Yangtze River Delta White Goats by Differential Display of mRNA

The study investigated the genetic basis for the formation of high-quality Type III Brush Hair in Yangtze River Delta white goats, which is used for making valuable writing brushes. Using differential display of mRNA, researchers identified seven cDNAs that influence the formation of this hair type. Among these, four were homologous to known genes: CMTM3, S100A4, PKIG, and fibulin 1-D, which were involved in hair growth and the hair follicle cycle. The findings provided insights into the molecular mechanisms behind the unique hair characteristics of these goats, contributing to the understanding of hair growth and follicle development.