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GlossaryComplementary DNA (cDNA)

form of DNA synthesized from an mRNA template

Complementary DNA (cDNA) is a form of DNA synthesized from a messenger RNA (mRNA) template in a process called reverse transcription. This type of DNA is often used in gene cloning or as a probe in the study of gene expression because it represents only the expressed genes of an organism, excluding non-coding regions.

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Characterization of a Partial cDNA for Lysyl Hydroxylase from Human Skin Fibroblasts; Lysyl Hydroxylase mRNAs Are Regulated Differently by Minoxidil Derivatives and Hydralazine

research Characterization of a Partial cDNA for Lysyl Hydroxylase from Human Skin Fibroblasts; Lysyl Hydroxylase mRNAs Are Regulated Differently by Minoxidil Derivatives and Hydralazine

46 citations, December 1992 in “Journal of Investigative Dermatology”

Minoxidil decreases LH expression, while hydralazine has mixed effects on prolyl and lysyl hydroxylase activities.

Characterization of a Cluster of Human High/Ultrahigh Sulfur Keratin-Associated Protein Genes Embedded in the Type I Keratin Gene Domain on Chromosome 17q12-21

research Characterization of a Cluster of Human High/Ultrahigh Sulfur Keratin-Associated Protein Genes Embedded in the Type I Keratin Gene Domain on Chromosome 17q12-21

98 citations, June 2001 in “Journal of biological chemistry/The Journal of biological chemistry”

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

research Skipping of Exons by Premature Termination of Transcription and Alternative Splicing Within Intron-5 of the Sheep SCF Gene: A Novel Splice Variant

6 citations, June 2012 in “PloS one”

A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.

research Evaluation of Short-Term Hair Follicle Storage Conditions for Maintenance of RNA Integrity

October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Hair follicles can be kept in RNAlater® at cool or room temperature for a week without harming RNA quality.

research Rapid Genetic Analysis of Epithelial-Mesenchymal Signaling During Hair Regeneration

6 citations, February 2013 in “Journal of Visualized Experiments”

The method quickly analyzes hair growth genes and shows that blocking Smo in skin cells stops hair growth.

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community 5 Months Results - Fin/Min/Keto Shampoo/Dermapen

in Progress Pictures 716 upvotes 2 years ago

Treatments for hair loss, including using finasteride and minoxidil regularly, together with keto shampoo and dermapen; the user's progress since starting treatment five months ago; and discussion of potential side effects.