Future Directions: Gene Polymorphism Diagnostics Relevant to Hair
January 2010
Research cited in this study
11 / 11 results
research Male Pattern Baldness: Current Treatments, Future Prospects
This review addresses the limited efficacy of current treatments for male pattern baldness and explains that emerging genetic insights could lead to more effective future therapies.
research EDA2R Is Associated With Androgenetic Alopecia
EDA2R gene linked to hair loss.
research Baldness And The Androgen Receptor: The AR Polyglycine Repeat Polymorphism Does Not Confer Susceptibility To Androgenetic Alopecia
In this study, researchers found that while the SNP rs6152 is strongly associated with androgenetic alopecia, the GGN triplet repeat is not, suggesting the causative variant is likely a non-coding one.
research Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia
Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.
research The E211 G>A Androgen Receptor Polymorphism Is Associated With a Decreased Risk of Metastatic Prostate Cancer and Androgenetic Alopecia
This study found that the AR-E211 A allele is associated with a lower risk of both metastatic prostate cancer and androgenetic alopecia in an Australian population.
research Hair Follicle Pigmentation: Mechanisms and Factors Influencing Melanin Production
This article reviews follicular melanogenesis, detailing how melanin synthesis and its regulation in hair follicles depend on a complex interplay of cellular and molecular mechanisms, but reports no new clinical findings.
research Evaluation and Treatment of Male and Female Pattern Hair Loss
This article reviews the historical developments in understanding and treating male pattern hair loss, emphasizing the role of dihydrotestosterone and 5α-reductase inhibitors, but reports no new clinical findings.
research Genetic Basis of Male Pattern Baldness
Male pattern baldness is largely genetic, linked to the androgen receptor gene, and may relate to certain health issues.
research Polymorphism of the Androgen Receptor Gene Is Associated with Male Pattern Baldness
This study found that specific genetic markers near the androgen receptor gene are significantly more common in men with male pattern baldness, suggesting a genetic component in its development.
research Genetic Analysis of Male Pattern Baldness and the 5α-Reductase Genes
This study found no significant genetic association between the 5α-reductase enzyme genes and male pattern baldness, suggesting a polygenic etiology rather than simple inheritance.
research The Inheritance Of Common Baldness: To Be Or Not To Be?
This study presents evidence suggesting that androgenetic alopecia is most likely inherited through a polygenic model, challenging the traditional view that it is caused by a simple Mendelian autosomal dominant gene.
Similar Research
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research Human Hair as a Testing Substrate in the Era of Precision Medicine: Potential Role of ‘Omics-Based Approaches
This review discusses the potential of using human hair proteomics for non-invasive diagnostic and forensic applications but reports no new results; the authors highlight areas needing further research.
research Forensic DNA Phenotyping
This paper discusses forensic DNA phenotyping, emphasizing its ability to infer visible traits from biological samples without reference samples, but notes ethical and legal concerns related to its use.
research Molecular Genetics of Human Hair Diseases
research Hair Protein Polymorphism and Its Application to Forensic Science Hair Comparison.
This review discusses the variability of hair protein keratin in forensic hair comparison, focusing on species identification and individual discrimination, but it reports no new results.
research Evaluation of the predictive capacity of DNA variants associated with straight hair in Europeans
This study found that specific DNA variants in the TCHH, WNT10A, and FRAS1 genes are associated with predicting straight hair in Europeans, showing high sensitivity but low specificity, especially using a neural networks approach.